COMT, catechol-O-methyltransferase, 1312

N. diseases: 622; N. variants: 47
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0030193
Disease: Pain
Pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 1554 196 0.600 None 0.958 120 10 2003 2020
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms 		phenotype Behavior and Behavior Mechanisms Sign or Symptom 421 120 0.100 None 0.929 14 4 2009 2018
CUI: C0030201
Disease: Pain, Postoperative
Pain, Postoperative 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 102 14 0.100 None 1.000 12 3 2006 2019
CUI: C0871189
Disease: Psychotic symptom
Psychotic symptom 		phenotype Sign or Symptom 86 21 0.100 None 0.917 12 1 1991 2019
CUI: C0596240
Disease: Cancer Pain
Cancer Pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 62 4 0.080 None 1.000 8 1 2005 2020
CUI: C0150055
Disease: Chronic pain
Chronic pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 207 19 0.060 None 1.000 6 1 2006 2019
CUI: C0027796
Disease: Neuralgia
Neuralgia 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases Sign or Symptom 767 16 0.050 None 0.800 5 1 2005 2019
CUI: C0233401
Disease: Psychiatric symptom
Psychiatric symptom 		phenotype Sign or Symptom 95 12 0.050 None 1.000 5 1 2005 2019
CUI: C0018681
Disease: Headache
Headache 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 338 75 0.040 None 1.000 4 1 2006 2013
CUI: C0015672
Disease: Fatigue
Fatigue 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 760 67 0.030 None 1.000 3 2 2008 2019
CUI: C0024031
Disease: Low Back Pain
Low Back Pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 88 11 0.030 None 1.000 3 2 2012 2017
CUI: C2215257
Disease: Acute postoperative pain
Acute postoperative pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 8 0.030 None 1.000 3 2013 2013
CUI: C0001726
Disease: Affective Symptoms
Affective Symptoms 		phenotype Behavior and Behavior Mechanisms Sign or Symptom 23 10 0.020 None 0.500 2 4 2009 2018
CUI: C0011991
Disease: Diarrhea
Diarrhea 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 632 63 0.020 None 0.500 2 2000 2014
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases Sign or Symptom 451 4 0.310 None 1.000 2 1 2016 2020
CUI: C0037011
Disease: Shoulder Pain
Shoulder Pain 		phenotype Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases Sign or Symptom 18 7 0.020 None 1.000 2 2008 2008
CUI: C0037317
Disease: Sleep disturbances
Sleep disturbances 		phenotype Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms Sign or Symptom 311 74 0.020 None 1.000 2 2017 2019
CUI: C0234133
Disease: Extrapyramidal sign
Extrapyramidal sign 		phenotype Sign or Symptom 116 7 0.020 None 1.000 2 1 2008 2009
CUI: C0003578
Disease: Apnea
Apnea 		phenotype Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases Sign or Symptom 262 11 0.010 None 1.000 1 2019 2019
CUI: C0004941
Disease: Behavioral Symptoms
Behavioral Symptoms 		group Behavior and Behavior Mechanisms Sign or Symptom 45 9 0.010 None 1.000 1 2006 2006
CUI: C0007859
Disease: Neck Pain
Neck Pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 29 3 0.010 None 1.000 1 2011 2011
CUI: C0009806
Disease: Constipation
Constipation 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 424 57 0.110 None 1.000 1 2018 2018
CUI: C0012833
Disease: Dizziness
Dizziness 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 64 14 0.010 None 1.000 1 2011 2011
CUI: C0013395
Disease: Dyspepsia
Dyspepsia 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 61 5 0.010 None 1.000 1 2008 2008
CUI: C0023222
Disease: Pain in lower limb
Pain in lower limb 		phenotype Sign or Symptom 31 2 0.010 None < 0.001 1 2014 2014